Spectrophotometric determination of lysozyme chloride in pharmaceutical preparations

摘要

A spectrophotometric method for the determination of lysozyme chloride was estab- lished by using the 0-sulfophenylfluorone (SPF)-titanium (IV) complex. This method can be used to determine about 10-200μg.10ml lysozyme chloride, and is about 2-times more sensitive than the Japanese Standards of Pharmaceutical Ingredients method. This was applied to assays of lysozyme chloride in pharmaceutical preparations (tablet, gra- nule, syrup, drysyrup, capsule and cold medicine).