Analysis of Mainstream and Sidestream Cigarette Smoke Particulate Matter by Laser Desorption Mass Spectrometry

摘要

Laser desorption ionization Fourier transform ion cyclo-ntron resonance mass spectrometry (LDI-FTICRMS) wasnused to investigate particulate matter (PM) associated withnmainstream (MSS) and sidestream cigarette smokesn(SSS). The high mass resolution and the high massnmeasurement accuracy allowed a molecular formula forneach detected signal in the 150 500 m/z range to benassigned. The high number of peaks observed in massnspectra required additional data processing to extractninformation. In this context, Kendrick maps and VannKrevelen diagrams were drawn. These postacquisitionntreatments were used to more easily compare differentncigarette smokes: (i) MSS from different cigarettes andn(ii) MSS and SSS from the same cigarette. In both ionndetection modes, most of the detected species were foundnto be attributed to C6-31H2 35N0 7O0 9 compounds. Thencompounds observed in the study of SSS appeared tonbe more unsaturated and less oxygenated than thosenobservedwhenMSSof thesamecigarettewasinvestigated.