A transient increase in CCK mRNA levels in hippocampus following audiogenic convulsions in audiogenic seizure-prone rats

摘要

1)The number of CCK mRNA-positive neurons in principal hippocampus of nor- mal rats was 34±5, which elevated markedly after a sin- gel(155±7, P < 0.01) or multiple convulsions(95± 8, P < 0.01). 2)CCK mRNA levels in multiple con- secutive convulsion rats were lower than that in a single convulsion rats(P < 0.01). The in- Creased number of CCK mRNA-positive neurons in hip- Pocampus may have important functional consequences in Convulsion-associated processes.