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首页> 外文期刊>Acta Pharmacologica Sinica >Effect of anti-digoxin antiserum on endoxin and membrane ATP ase activity in hypoxia-reoxygenation induced myocardial injury
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Effect of anti-digoxin antiserum on endoxin and membrane ATP ase activity in hypoxia-reoxygenation induced myocardial injury

机译:抗地高辛抗血清对缺氧复氧性心肌损伤中内毒素和膜ATPase活性的影响

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摘要

The level of endoxin was remarkably high- er, ATPase activities in cell membrane were remarkably lower in hypoxic group and hypoxia-reoxygenation injury group than those of normal group; anti-digoxin antiserum could resume ATPase activity in a concentration-depen- dent manne. Rise of endoxin was the Molecular biological basis of myocardial damage during Myocardial hypoxia-reoxygenation. Anti-digoxin anti- Serum had lessened myocardial injury and had a protective Effect on hypoxia-reoxygenation myocardium by antgao- Nizing effect of endoxin.
机译:缺氧组和缺氧复氧损伤组的内毒素水平明显升高,细胞膜ATPase活性明显低于正常组。抗地高辛抗血清可以在浓度依赖性的曼尼中恢复ATPase活性。内毒素的升高是心肌缺氧-复氧过程中心肌损伤的分子生物学基础。抗地高辛抗血清可通过内毒素的抗胃酸作用减轻心肌损伤,并对缺氧-复氧心肌有保护作用。

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