Effect of hepatocyte growth-promoting factor and panax notogin- seng saponins on intrasplenic hepatocellular autotransplantation

摘要

(1)Hepatocellular degeneration was slightly less in group B[intrasplenic hepatocyte autolo- gous transplantation(IHAT) + PNGS 25 mg/kg, im, qd] vs the control group(group C, IHAT without drugs) at the 2nd week after transplantation, and the ALT con- tent of group B(928U/g ±268U/g)was higher than that of group C(639U/g ±138U/g, P < 0.01). PHGF has effects in in- Creasing the weight of liver tissue growth in spleen and Shortening the regeneration period of the transplanted hep- Atocytes, while PNGS has certain effects on protenting the Hepatocytes against ischemic-reperfusion injury in the ear- Ly stage of transplantation.