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Autism‐Related Variation in Reciprocal Social Behavior: A Longitudinal Study

机译:互惠社会行为中与自闭症相关的变异:一项纵向研究

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摘要

Deficits in reciprocal social behavior are a characterizing feature of autism spectrum disorder (ASD). Autism‐related variation in reciprocal social behavior (AVR) in the general population is continuously distributed and highly heritable—a function of additive genetic influences that overlap substantially with those which engender clinical autistic syndromes. This is the first long‐term prospective study of the stability of AVR from childhood through early adulthood, conducted via serial ratings using the Social Responsiveness Scale, in a cohort‐sequential study involving children with ASD, other psychiatric conditions, and their siblings (N = 602, ages = 2.5–29). AVR exhibits marked stability throughout childhood in individuals with and without ASD.
机译:互惠的社会行为的不足是自闭症谱系障碍(ASD)的特征。普通人群中与自闭症相关的互惠社会行为变异是连续分布且高度可遗传的-附加遗传影响的功能与引起自闭症的显着重叠。这是一项关于AVR从儿童期到成年早期的稳定性的长期长期前瞻性研究,该研究使用社会反应能力量表通过系列评分进行,这是一项队列研究,涉及患有ASD,其他精神疾病及其兄弟姐妹的儿童(N = 602,年龄= 2.5–29)。在有和没有ASD的个体中,AVR在整个儿童时期都表现出明显的稳定性。

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