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Introduction to the Special Issue Pathways Between Genes Brain and Behavior

机译:特刊简介基因大脑与行为之间的途径

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摘要

In the past 10 years or so, with the sequencing of the human genome and rapid advances in the development of high throughput techniques, the field of behavior genetics has increasingly moved toward the detection of actual genes and environmental factors. However, the field is still in the relatively early stages of understanding some of the basic facts about the complex genetic underpinnings of brain structure and function and their relationship to behavior. The 15 articles in this special issue were selected to represent the diversity of methodologies applied to the complexity of pathways linking genes, brain, and behavior. While providing strong evidence for the role of genes in individual differences in brain structure and function, these papers also demonstrate that environmental experiences alter neurobiological pathways, and that genetic factors may further moderate the impact of environmental experience. Most importantly, the breadth of studies proves that in order to be able to trace the pathways between genes, brain, and behavior, we need experts in genetics, neuroscience, psychology, and psychiatry.
机译:在过去的十年左右的时间里,随着人类基因组测序的发展以及高通量技术的飞速发展,行为遗传学领域已逐渐转向检测实际基因和环境因素。但是,该领域仍处于了解大脑结构和功能的复杂遗传基础及其与行为关系的一些基本事实的相对早期阶段。选择本期特刊中的15篇文章来代表适用于连接基因,大脑和行为的途径复杂性的方法论的多样性。这些论文为基因在个体大脑结构和功能差异中的作用提供了有力的证据,同时还证明环境经历改变了神经生物学途径,遗传因素可能进一步减轻环境经历的影响。最重要的是,研究的广度证明,为了能够追踪基因,大脑和行为之间的通路,我们需要遗传学,神经科学,心理学和精神病学方面的专家。

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