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Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered

机译：小鼠中与骨负荷硬化蛋白表达有关的机械负荷相关变化比随后产生的峰值毒株与随后的成骨反应更紧密相关

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SummaryOsteocyte sclerostin is regulated by loading and disuse in mouse tibiae but is more closely related to subsequent local osteogenesis than the peak strains engendered.

机译：总结骨胫骨中的负载和不使用可调节骨水泥硬化素，但与随后产生的峰值应变相比，骨水泥硬化素与随后的局部成骨作用更紧密相关。

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期刊名称 Springer Open Choice
作者
A. Moustafa; T. Sugiyama; J. Prasad; G. Zaman; T. S. Gross; L. E. Lanyon; J. S. Price;
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作者单位

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年(卷),期 -1(23),4
年度 -1
页码 1225–1234
总页数 10
原文格式 PDF
正文语种
中图分类外科学;
关键词
Disuse Finite element analysis Mechanical loading Mechanical strain Osteocyte Sclerostin;

机译：废弃;有限元分析;机械载荷;机械应变;骨细胞;硬化蛋白;

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专利

1. Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered. [J] . A Moustafa, T Sugiyama, J Prasad, Osteoporosis international: a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA . 2012,第4期

机译：与产生的峰值菌株相比，小鼠中骨细胞硬化素表达中与机械负荷相关的变化与随后的成骨反应更紧密相关。
2. Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered [J] . A. Moustafa, T. Sugiyama, J. Prasad, Osteoporosis International . 2012,第4期

机译：小鼠中与骨负荷硬化蛋白表达有关的机械负荷相关变化比随后产生的峰值毒株与随后的成骨反应更紧密相关
3. Mechanical stimulation in vivo reduces osteocyte expression of sclerostin [J] . A.G. Robling, T. Bellido, C.H. Turner The Journal of Musculoskeletal and Neuronal Interactions . 2006,第4期

机译：体内机械刺激可减少硬化素的骨细胞表达
4. Differential Expression of Sclerostin Between Juvenile and Adult Mice [C] . M.D. KWAN, D.M. GUPTA, BJ. SLATER, International Society of Craniofacial Surgery . 2007

机译：少年和成人小鼠之间菌丝蛋白的差异表达
5. Osteocyte Signalling in Response to Mechanical Loading after Physical Cellular Damage and Hyperglycemia. [D] . Liu, Chao. 2016

机译：物理细胞损伤和高血糖后机械负荷响应中的骨细胞信号传递。
6. The Wnt Inhibitor Sclerostin Is Up-regulated by Mechanical Unloading in Osteocytes in Vitro [O] . Jordan M. Spatz, Marc N. Wein, Jonathan H. Gooi, 2015

机译：Wnt抑制剂硬化蛋白通过体外骨细胞的机械卸载而上调。
7. Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered [O] . A. Moustafa, T. Sugiyama, J. Prasad, 2011

机译：小鼠中与骨负荷硬化蛋白表达有关的机械负荷相关变化比随后产生的峰值毒株与随后的成骨反应更紧密相关
8. NSAIDS and the Osteogenic Response to Mechanical Stress in Premenopausal Women [R] . Kohrt, W. , Schwartz, R. S. 2007

机译：NsaIDs与绝经前妇女机械应激的成骨反应

Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered

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