Isolated and Spontaneous Correction of Proximal Interphalangeal Joint Contractures in Dupuytren’s Disease: An Exploratory Analysis of the Efficacy and Safety of Collagenase Clostridium histolyticum

摘要

Background and ObjectiveDupuytren’s contractures affecting proximal interphalangeal (PIP) joints are challenging to treat. We explored the effects of collagenase Clostridium histolyticum (CCH) on PIP joint contractures after injection of an affected metacarpophalangeal (MP) joint in the same finger and after injection of an isolated PIP joint contracture.