Effects of Tiotropium Combined with Theophylline on Stable COPD Patients of Group B D and its Impact on Small Airway Function: A Randomized Controlled Trial

摘要

IntroductionTiotropium bromide has been widely used in clinical practice, while theophylline is another treatment option for chronic obstructive pulmonary disease (COPD). However, only a few relevant studies have investigated the long-term outcomes and efficacy of both in patients with COPD. We evaluated the effects of tiotropium and low-dose theophylline on stable COPD patients of groups B and D.