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Community-Based Antiretroviral Therapy (ART) Delivery for Female Sex Workers in Tanzania: 6-Month ART Initiation and Adherence

机译:坦桑尼亚为女性工作者提供的基于社区的抗逆转录病毒疗法(ART):6个月的ART启动和坚持治疗

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摘要

We conducted an implementation science study of a community-based ART distribution program for HIV-positive female sex workers (FSW) whereby clients received ART services through community-based mobile and home-based platforms. We compared 6-month treatment-related outcomes in the community-based ART arm (N = 256) to the standard facility-based ART delivery arm (N = 253). Those in the intervention arm were more likely to have initiated ART (100.0% vs. 71.5%; p = 0.04), be currently taking ART at the 6-month visit (100.0% vs. 95.0%; p < 0.01), and less likely to have stopped taking ART for more than 30 days continuously (0.9% vs. 5.7%; p = 0.008) or feel high levels of internalized stigma (26.6% vs. 39.9%; p = 0.001). In the adjusted regression model, internalized stigma (adjusted OR [aOR]: 0.5; 95% CI 0.28–0.83) and receiving community-based ART (aOR: 208.6; 95% CI 12.5–3479.0) were significantly associated with ART initiation. Community-based ART distribution model can improve linkage to and adherence to ART over standard facility-based ART programs for FSWs.
机译:我们进行了一项针对艾滋病毒阳性女性性工作者(FSW)的社区ART分发计划的实施科学研究,该项目使客户通过基于社区的移动和家庭平台获得ART服务。我们将以社区为基础的抗逆转录病毒治疗组(N = 256)与基于标准设施的抗病毒治疗分娩(N = 253)的六个月治疗相关结局进行了比较。介入治疗组的患者更可能开始接受抗逆转录病毒治疗(100.0%vs. 71.5%; p = 0.04),目前在六个月的随访中接受抗逆转录病毒治疗(100.0%vs. 95.0%; p <0.01),并且更少可能已经连续30天以上停止服用抗逆转录病毒药物(0.9%vs.5.7%; p = 0.008)或感到较高的内在耻辱感(26.6%vs. 39.9%; p = 0.001)。在调整后的回归模型中,内在的耻辱感(调整后的OR [aOR]:0.5; 95%CI 0.28–0.83)和接受基于社区的抗逆转录病毒疗法(aOR:208.6; 95%CI 12.5–3479.0)与抗逆转录病毒治疗显着相关。基于社区的ART分发模型可以改善针对FSW的基于设施的标准ART程序与ART的链接和依从性。

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