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A bioeconomic model for the optimization of local canine rabies control

机译:优化本地犬狂犬病控制的生物经济模型

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摘要

We present a new modeling tool that can be used to maximize the impact of canine rabies management resources that are available at the local level. The model is accessible through a web-based interface that allows for flexibility in the management strategies that can be investigated. Rabies vaccination, sterilization, chemo-contraception, and euthanasia can be specified and limited to specific demographic groups. Additionally, we allowed for considerable complexity in the specification of management costs. In many areas, the costs of contacting additional dogs increases as management effort increases, and this can have important strategic implications. We illustrated the application of the model by examining several alternative management strategies in an area of Mpumalanga Province, South Africa. Our results based on this dog population suggested that puppies should be vaccinated and sterilization would not be optimal if the spatial extent of management is not large (and perhaps not even then). Furthermore, given a sufficient budget, it was evident that vaccination campaigns should be repeated annually.
机译:我们提供了一个新的建模工具,可用于最大程度地提高本地级别的犬狂犬病管理资源的影响。可通过基于Web的界面访问该模型,该界面可灵活地管理可调查的管理策略。可以指定狂犬病的疫苗接种,绝育,化学避孕和安乐死,并且仅限于特定的人群。此外,我们在管理成本的说明中考虑了相当大的复杂性。在许多地区,随着管理工作量的增加,接触更多犬只的成本也会增加,这可能具有重要的战略意义。我们通过研究南非姆普马兰加省地区的几种替代管理策略来说明该模型的应用。我们根据这种狗的数量得出的结果表明,如果管理的空间范围不大(甚至可能不那么大),则应该给幼犬接种疫苗,并且绝育效果不是最佳的。此外,在有足够预算的情况下,很明显应该每年进行一次疫苗接种运动。

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