A Risk-Factor Guided Approach to Reducing Lactic Acidosis andHyperlactatemia in Patients on Antiretroviral Therapy

摘要

BackgroundStavudine continues to be used in antiretroviral treatment (ART) regimens in many resource-limited settings. The use of zidovudine instead of stavudine in higher-risk patients to reduce the likelihood of lactic acidosis and hyperlactatemia (LAHL) has not been examined.