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Bovine Hemoglobin-Based Oxygen Carrier as Pump Prime for Cardiopulmonary Bypass: Reduced Systemic Lactic Acidosis and Improved Cerebral Oxygen Metabolism During Low-flow in a Porcine Model

机译：基于牛血红蛋白的氧载体作为体外循环的泵浦素：在猪模型中低流量期间减少系统性乳酸酸中毒和改善脑氧代谢

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This document is the final report for the research project 'Evaluation of Hemopure (HBOC-201) during cardiopulmonary bypass in domesticated swine (sus scrufa)' funded by AF Surgeon General. This final report will be published in the Journal of Thoracic and Cardiovascular Surgery, details TBD.

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McNeil, J. D.; Propper, B.; Walker, J.; Holguin, L.; Evans, L.;
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年度 2010
页码 1-26
总页数 26
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Bovines ; Hemoglobin ; Cardiology ; Cardiovascular system ; Physicians ; Surgery ; Blood substitutes ; Cerebrum ; Swine ; Acidosis ; Pulmonary blood circulation ; Oxygen ; Reduction ; Lactic dehydrogenase ; Models ; Metabolism;

机译：牛;血红蛋白;心脏病学;心血管系统;内科医生;外科手术;血液替代品;大脑;猪;酸中毒;肺血液循环;氧气;还原;乳酸脱氢酶;模型;代谢;
入库时间 2022-08-29 10:53:58

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1. A bovine hemoglobin-based oxygen carrier as pump prime for cardiopulmonary bypass: reduced systemic lactic acidosis and improved cerebral oxygen metabolism during low flow in a porcine model. [J] . McNeil JD, Propper B, Walker J, The Journal of Thoracic and Cardiovascular Surgery . 2011,第2期

机译：一种基于牛血红蛋白的氧气载体，可作为体外循环的泵送泵：在猪模型中，在低流量时可减少系统性乳酸酸中毒并改善脑氧代谢。
2. A bovine hemoglobin-based oxygen carrier as pump prime for cardiopulmonary bypass: Reduced systemic lactic acidosis and improved cerebral oxygen metabolism during low flow in a porcine model [J] . Jeffrey D. McNeil, Brandon Propper, Joshua Walker, The journal of thoracic and cardiovascular surgery . 2011,第2期

机译：以牛血红蛋白为基础的氧气载体作为体外循环的主要泵浦剂：在猪模型中，低流量时系统性乳酸酸中毒减少，脑氧代谢改善
3. Hemoglobin-based oxygen carrier attenuates cerebral damage by improving tissue oxygen preload in a dog model of cardiopulmonary bypass [J] . Li Qian, Li Shen, Yang Qian, Artificial cells, nanomedicine, and biotechnology. . 2015,第1a6期

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4. Monitoring Cerebral Oxygen Saturation Using Near Infrared Spectroscopy during Cardiopulmonary Bypass: Comparing with Monitoring Mixed Venous Oxygen Saturation [C] . Teng Yichao, Ding Haishu, Huang Lan, 2007 IEEE/ICME INTERNATIONAL CONFERENCE ON COMPLEX MEDICAL ENGINEERING . 2007

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5. High oxygen affinity polymerized bovine hemoglobin-based oxygen carriers as potential artificial blood substitutes. [D] . Eike, Julie Hughes. 2005

机译：高氧亲和力聚合牛血红蛋白基氧载体作为潜在的人工血液替代品。
6. Effects of a Hemoglobin-Based Oxygen Carrier (HBOC-201) and Derivatives with Altered Oxygen Affinity and Viscosity on Systemic and Microcirculatory Variables in a Top-load Rat Model [O] . Bjorn Kyungsuck Song, William H. Nugent, Paula F. Moon-Massat, -1

机译：基于血红蛋白的氧气载体（HBOC-201）及其氧亲和力和粘度改变的衍生物对最大负荷大鼠模型系统和微循环变量的影响
7. A bovine hemoglobin-based oxygen carrier as pump prime for cardiopulmonary bypass: Reduced systemic lactic acidosis and improved cerebral oxygen metabolism during low flow in a porcine model [O] . McNeil Jeffrey D., Propper Brandon, Walker Joshua, 2011

机译：以牛血红蛋白为基础的氧气载体作为体外循环的主要泵浦剂：在猪模型中，低流量时系统性乳酸酸中毒减少，脑氧代谢改善

Bovine Hemoglobin-Based Oxygen Carrier as Pump Prime for Cardiopulmonary Bypass: Reduced Systemic Lactic Acidosis and Improved Cerebral Oxygen Metabolism During Low-flow in a Porcine Model

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