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No Association of PTPN22 Polymorphisms with Susceptibility to Ocular Behcet's Disease in Two Chinese Han Populations

机译:PTPN22基因多态性与中国汉族人群眼白塞氏病的易感性没有关联

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摘要

BackgroundBehcet's disease is known as a recurrent, multisystem inflammation and immune-related disease. Protein tyrosine phosphatase non-receptor 22 (PTPN22) is a key negative regulator of T lymphocytes and polymorphisms of the PTPN22 gene have been shown to be associated with various immune-related diseases. The present study was performed to assess the association between PTPN22 polymorphisms and Behcet's disease in two Chinese Han populations.
机译:背景贝塞特氏病被称为复发性多系统炎症和免疫相关疾病。蛋白质酪氨酸磷酸酶非受体22(PTPN22)是T淋巴细胞的关键负调节剂,并且已显示PTPN22基因的多态性与多种免疫相关疾病有关。本研究旨在评估中国两个汉族人群中PTPN22基因多态性与Behcet病之间的关系。

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