Facilitating Tumor Functional Assessment by Spatially Relating 3D Tumor Histology and In Vivo MRI: Image Registration Approach

摘要

BackgroundMagnetic resonance imaging (MRI), together with histology, is widely used to diagnose and to monitor treatment in oncology. Spatial correspondence between these modalities provides information about the ability of MRI to characterize cancerous tissue. However, registration is complicated by deformations during pathological processing, and differences in scale and information content.