1452. Non-invasive Pneumococcal Pneumonia in Adults in Portugal: Continued Decline of PCV13 Serotypes (2015–2017)

摘要

BackgroundIn 2015, PCV13 was introduced in the National Immunization Plan in Portugal for children, although it was not significantly used in adults. However, changes in the pneumococcal population causing non-invasive pneumococcal pneumonia (NIPP) in adults (≥18 years) can occur due to herd effects. To evaluate this, we monitored the serotypes and antimicrobial resistance of adult NIPP isolates in 2015–2017. >Methods. A total of 1,142 isolates were recovered, serotyped by Quellung and tested for susceptibility to antimicrobials by disk diffusion or Etest.