221. Save the Quinolones! Impact of a Non-Restrictive Fluoroquinolone Reduction Initiative on Antibiotic Resistance at an Urban Teaching Hospital

摘要

BackgroundThe use of fluoroquinolones, one of the most commonly used antibiotic classes in the United States, is associated with adverse drug events, Clostridium difficile infection and antibiotic resistance in Staphylococcus aureus and other Gram-negative bacilli. Many hospitals have instituted resource-intensive interventions to minimize fluoroquinolone use. In hospital settings with fewer resources, education and awareness campaigns offer a more feasible approach. The purpose of this study was to assess the impact of a nonrestrictive fluoroquinolone reduction initiative on institutional antibiotic resistance.