Assessing transmissibility of HIV-1 drug resistance mutations from treated and from drug-naive individuals

摘要

Objectives:Surveillance drug resistance mutations (SDRMs) in drug-naive patients are typically used to survey HIV-1-transmitted drug resistance (TDR). We test here how SDRMs in patients failing treatment, the original source of TDR, contribute to assessing TDR, transmissibility and transmission source of SDRMs.