In eukaryotic cell division, the kinetochore mediates chromosome attachment to spindle microtubules and acts as a scaffold for signaling pathways, ensuring the accuracy of chromosome segregation. The architecture of the kinetochore underlies its function in mitosis. In this issue, Hornung et al. (2014. J. Cell Biol. ) identify an unexpected linkage between the inner and outer regions of the kinetochore in budding yeast that suggests a new model for the construction of this interface.
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机译：在真核细胞分裂中，线粒体介导染色体附着于纺锤体微管，并充当信号传导途径的支架，确保染色体分离的准确性。线粒体的结构为其在有丝分裂中的功能奠定了基础。在本期中，Hornung等人。 （2014. J. Cell Biol。）鉴定了发芽酵母中线粒体内部和外部区域之间的意外连接，这为构建该界面提供了新模型。
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