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Characterisation of Benzodiazepine Use in an Older Population Registered in Family Health Units in the Region of Minho Portugal

机译:在葡萄牙米尼奥地区家庭卫生部门登记的老年人口中使用苯二氮卓类药物的特性

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摘要

Benzodiazepines are the most frequently consumed psychotropic drugs among older persons. This pharmacological class has been advised against in this group, due to the various risks associated with its use in an older population. This study seeks to determine the prevalence of benzodiazepine use in a non-institutionalized older population over the age of 75 that is registered in Family Health Units (USF) in the region of Minho, Portugal, as well as to characterize these patients and understand the link between benzodiazepine use and chronic medication use, risk of falls, and level of physical and functional dependence. The data extracted from the clinical records registered in the SAM® were analyzed using the Statistical Package for the Social Sciences (SPSS). A sample of 700 patients was obtained. These patients presented a mean age of 82.3 years, 62.7% were female, 95.3% were physically independent, and 38.0% were functionally independent. Almost half of the elder persons presented a moderate (36.9%) or high (11.4%) risk of falls. 37.9% of the patients were chronic benzodiazepines users, using between 1 and 3 active substances belonging to this pharmacological class, with a higher rate of use among women (p < 0.001) and elder persons. There was a statistically significant association among the use of benzodiazepines, a functional independence, and a higher risk of falls. These pioneering findings in Portugal reveal a high prevalence of benzodiazepine use in the population studied and warn about the specific characteristics of said population and the importance in reducing the risks associated with the inappropriate prescription of these drugs.
机译:苯二氮卓类药物是老年人中最常用的精神药物。由于在老年人群中使用该药会有各种风险,因此不建议在此组中使用该药理学类别。本研究旨在确定在葡萄牙米尼奥地区的家庭保健单位(USF)注册的75岁以上非机构化老年人群中苯二氮卓类药物的使用率,以及对这些患者进行特征分析和了解苯二氮卓类药物使用与长期用药,跌倒的风险以及身体和功能依赖性水平之间的联系。使用社会科学统计软件包(SPSS)分析从SAM ®中注册的临床记录中提取的数据。获得了700名患者的样本。这些患者的平均年龄为82.3岁,女性为62.7%,身体独立为95.3%,功能独立为38.0%。几乎一半的老年人出现中度跌倒的风险(36.9%)或高(11.4%)。 37.9%的患者是慢性苯二氮卓类药物的使用者,使用了这种药理学类别的1至3种活性物质,在女性(p <0.001)和老年人中使用率更高。在使用苯二氮卓类药物,功能独立性和较高的跌倒风险之间存在统计学上的显着关联。葡萄牙的这些开创性发现表明,在研究的人群中苯二氮卓类药物的使用率很高,并警告了该人群的具体特征,以及在减少与不适当处方这些药物有关的风险方面的重要性。

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