Transcriptional analysis identifies key genes involved in metabolism fibrosis/tissue repair and the immune response against Fasciola hepatica in sheep liver

摘要

BackgroundAlthough fascioliasis has been relatively well studied, little is known about the molecular basis of this disease. This is particularly relevant, considering the very different response that sheep have to Fasciola hepatica relative to cattle. The acute phase of this disease is severe in sheep, whereas chronic fascioliasis is more common in cattle.