Ruthenium- and osmium-arene complexes of 8-substituted indolo32-cquinolines: Synthesis X-ray diffraction structures spectroscopic properties and antiproliferative activity

摘要

Graphical abstractSix novel ruthenium(II)- and osmium(II)-arene complexes with indoloquinoline modified ligands containing methyl and halo substituents in position 8 of the molecule backbone have been synthesised, comprehensively characterised and tested for cytotoxicity in three human cancer cell lines, yielding IC50 values in the 10⁻⁶–10⁻⁷ M concentration range.