Extramedullary plasmacytoma as a mode of relapse in multiple myeloma (MM) is unusual. Current recommendations do not incorporate the routine use of 18-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET/CT) imaging prior to haematopoietic stem cell transplant (HSCT) in MM. We report a case of relapsed MM with complete remission as per IMWG criteria. In the interim period, before the HSCT, the patient had localizing neurological signs and symptoms attributed to multiple extramedullary plasmacytomas. The uniqueness of this case is that this patient after complete marrow remission with no obvious external masses had unexpected, symptomatic multiple extramedullary plasmacytomas. This case illustrates the need for integration of FDG PET/CT imaging into routine pre-HSCT investigations in relapsed MM to prevent missing any asymptomatic extramedullary plasmacytomas.
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机译：髓外浆细胞瘤是多发性骨髓瘤（MM）复发的一种方式。当前的建议未将MM造血干细胞移植（HSCT）之前常规使用18-氟脱氧葡萄糖正电子发射断层扫描计算机断层扫描（FDG PET / CT）成像。我们按照IMWG标准报告了完全缓解的MM复发病例。在HSCT之前的过渡时期，患者出现了局部神经系统症状和症状，这些症状和症状归因于多个髓外浆细胞瘤。该病例的独特性在于该患者在完全缓解后，没有明显的外部肿块，出现了意料之外的，症状性的多个髓外浆细胞瘤。该病例说明需要将FDG PET / CT成像整合到复发性MM中的常规HSCT前检查中，以防止遗漏任何无症状的髓外浆细胞瘤。
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