An Efficient Total Synthesis of a Potent Anti-Inflammatory Agent Benzocamphorin F and Its Anti-Inflammatory Activity

摘要

A naturally occurring enynyl-benzenoid, benzocamphorin F (>1), from the edible fungus Taiwanofungus camphoratus (Antrodia camphorata) was characterized by comprehensive spectral analysis. It displays anti-inflammatory bioactivity and is valuable for further biological studies. The present study is the first total synthesis of benzocamphorin F and the developed strategy described is a more efficient procedure that allowe the large-scale production of benzocamphorin F for further research of the biological activity both in vitro and in vivo.