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Electrical Activity of the Bladder Is Attenuated by Intravesical Inhibition of P2X2/3 Receptors During Micturition in Female Rats

机译：雌性大鼠排尿过程中膀胱内P2X2 / 3受体的膀胱抑制作用减弱了膀胱的电活动。

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摘要

PurposeTo simultaneously monitor electrical discharges in various bladder regions and the external urethral sphincter (EUS) during voiding contractions, and to assess the functional role of myogenic modulation of the lower urinary tract (LUT) by ionotropic purinergic receptors containing the P2X3 subunit.

机译：目的同时监测排尿收缩期间各个膀胱区域和外部尿道括约肌（EUS）的放电，并评估包含P2X3亚基的离子性嘌呤能受体对下尿路（LUT）的肌源性调节的功能作用。

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期刊名称 International Neurourology Journal
作者
Betsy H. Salazar; Kristopher A. Hoffman; Chuan Zhang; Alex Kavanagh; Yingchun Zhang; Timothy B. Boone; Alvaro Munoz;
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作者单位

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年(卷),期 2017(21),4
年度 2017
页码 259–269
总页数 11
原文格式 PDF
正文语种
中图分类神经科学 ;
关键词
Lower Urinary Tract Symptoms Urination Purinergic P2X Receptor Antagonists Urinary Bladder Electrophysiology;

机译：下尿路症状;排尿;嘌呤能P2X受体拮抗剂;膀胱膀胱电生理;

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专利

1. Electrical Activity of the Bladder Is Attenuated by Intravesical Inhibition of P2X2/3 Receptors During Micturition in Female Rats [J] . Betsy H. Salazar, Kristopher A. Hoffman, Chuan Zhang, International Neurourology Journal . 2017 ,第4期

机译：雌性大鼠排尿过程中膀胱内P2X2 / 3受体的膀胱抑制抑制膀胱的电活动。
2. Modulatory effects of intravesical P2X2/3 purinergic receptor inhibition on lower urinary tract electromyographic properties and voiding function of female rats with moderate or severe spinal cord injury [J] . Salazar Betsy H., Hoffman Kristopher A., Zhang Chuan, BJU international . 2019 ,第3期

机译：膀胱内P2X2 / 3嘌呤能受体抑制对中等或严重脊髓损伤的雌性大鼠降低尿路肌电视性能和空隙功能的调节作用
3. 5-HT 2A receptor activation of the external urethral sphincter and 5-HT 2C receptor inhibition of micturition: A study based on pharmacokinetics in the anaesthetized female rat [J] . MbakiY., GardinerJ., McMurrayG., European Journal of Pharmacology: An International Journal . 2012 ,第1a3期

机译：外尿道括约肌的5-HT 2A受体激活和分泌术的5-HT 2C受体抑制：基于药代动力学在麻醉雌性大鼠中的研究
4. In vivo fluorescence imaging of an orthotopic rat bladder tumor model indicates differential uptake of intravesically instilled near-infrared labeled 2-deoxyglucose analog by neoplastic urinary bladder tissues [C] . Daqing Piao, Carole A. Davis, Robert E. Hurst, Therapeutics and Diagnostics in Urology: Lasers, Robotics, Minimally Invasive, and Advanced Biomedical Devices . 2017

机译：原位大鼠膀胱肿瘤模型的体内荧光成像显示肿瘤性膀胱组织对膀胱内滴注的近红外标记的2-脱氧葡萄糖类似物的摄取差异
5. Inhibition of interleukin-2 secretion by 2-arachidonyl glycerol and anandamide occurs through peroxisome proliferator activated receptor gamma independently of the cannabinoid receptors. [D] . Rockwell, Cheryl Elizabeth. 2005

机译：2-花生四烯酸基甘油和anandamide对白介素2分泌的抑制作用是通过过氧化物酶体增殖物激活的受体γ来实现的，而与大麻素受体无关。
6. Oxytocin Reduces Intravesical Pressure in Anesthetized Female Rats: Action on Oxytocin Receptors of the Urinary Bladder [O] . Eduardo M. Cafarchio, Luiz A. da Silva, Luciana C. Auresco, 2020

机译：催产素降低麻醉的雌性大鼠的膀胱内压力：对膀胱膀胱催产素受体的作用
7. Electrical Activity of the Bladder Is Attenuated by Intravesical Inhibition of P2X2/3 Receptors During Micturition in Female Rats [O] . Betsy H. Salazar, Kristopher A. Hoffman, Chuan Zhang, 2017

机译：通过在雌性大鼠的尿尿中的尿尿过程中的P2x2 / 3受体的膀胱内抑制来衰减膀胱的电活性

Electrical Activity of the Bladder Is Attenuated by Intravesical Inhibition of P2X2/3 Receptors During Micturition in Female Rats

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