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Update on the management of acute pharyngitis in children

机译:儿童急性咽炎的处理最新情况

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摘要

Streptococcal pharyngitis is a very common pathology in paediatric age all over the world. Nevertheless there isn't a joint agreement on the management of this condition. Some authors recommend to perform a microbiological investigation in suspected bacterial cases in order to treat the confirmed cases with antibiotics so to prevent suppurative complications and acute rheumatic fever. Differently, other authors consider pharyngitis, even streptococcal one, a benign, self-limiting disease. Consequently they wouldn't routinely perform microbiological tests and, pointing to a judicious use of antibiotics, they would reserve antimicrobial treatment to well-selected cases. It has been calculated that the number of patients needed to treat to prevent one complication after upper respiratory tract infections (including sore throat), was over 4000.Even the use of the Centor score, in order to evaluate the risk of streptococcal infection, is under debate and the interpretation of the test results may vary considerably. Penicillin is considered all over the world as first line treatment, but oral amoxicillin is also accepted and, due to its better palatability, can be a suitable option. Macrolides should be reserved to the rare cases of proved allergy to β-lactams. Cephalosporins can be used in patients allergic to penicillin (with the exception of type I hypersensibility) and have been also proposed to treat the relapses.
机译:链球菌性咽炎是全世界儿童年龄中非常常见的病理。但是,对于这种情况的管理尚无共同协议。一些作者建议对可疑细菌病例进行微生物学调查,以便用抗生素治疗确诊的病例,以防止化脓性并发症和急性风湿热。不同的是,其他作者认为咽炎(甚至是链球菌性咽炎)是一种良性的自限性疾病。因此,他们不会常规进行微生物检测,并指出明智地使用抗生素,他们会为精选的病例保留抗菌治疗。据计算,预防上呼吸道感染(包括喉咙痛)后发生一种并发症所需治疗的患者人数超过4000.即使使用Centor评分来评估链球菌感染的风险辩论中,测试结果的解释可能会有很大差异。青霉素在世界范围内被认为是一线治疗,但口服阿莫西林也被接受,由于其更好的适口性,可能是合适的选择。大环内酯类药物应保留用于对β-内酰胺类过敏的罕见情况。头孢菌素可用于对青霉素过敏的患者(I型超敏反应除外),并已提出治疗复发的建议。

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