Rescue of arterial function by angiotensin-(1-7): towards improvement of endothelial function by drug-eluting stents

摘要

Purpose:To explore the hypothesis that stent placement decreases dilator function of various arteries outside the stented segment and that angiotensin- (1-7) improves this function, and to assess the contribution of dilator signal compounds. A further objective was to test the hypothesis that on-stent delivery of Ang-(1-7) reduces neointima formation and improves endothelial function.