Regulation of the Intercellular Adhesin Locus Regulator (icaR) by SarA σB and IcaR in Staphylococcus aureus

摘要

The staphylococcal accessory regulator SarA and the alternative sigma factor σ^B have been previously identified as positive regulators, and IcaR as a negative regulator, of icaADBC expression. Here, we show that in Staphylococcus aureus SarA and σ^B are also required for icaR expression and that IcaR does not have a significant effect on its own expression.