OpenTox predictive toxicology framework: toxicological ontology and semantic media wiki-based OpenToxipedia

摘要

BackgroundThe OpenTox Framework, developed by the partners in the OpenTox project (), aims at providing a unified access to toxicity data, predictive models and validation procedures. Interoperability of resources is achieved using a common information model, based on the OpenTox ontologies, describing predictive algorithms, models and toxicity data. As toxicological data may come from different, heterogeneous sources, a deployed ontology, unifying the terminology and the resources, is critical for the rational and reliable organization of the data, and its automatic processing.