Anticancer Activity of Cobra Venom Polypeptide Cytotoxin-II against Human Breast Adenocarcinoma Cell Line (MCF-7) via the Induction of Apoptosis

摘要

PurposeBreast cancer is a significant health problem worldwide, accounting for a quarter of all cancer diagnoses in women. Current strategies for breast cancer treatment are not fully effective, and there is substantial interest in the identification of novel anticancer agents especially from natural products including toxins. Cytotoxins are polypeptides found in the venom of cobras and have various physiological effects. In the present study, the anticancer potential of cytotoxin-II against the human breast adenocarcinoma cell line (MCF-7) was investigated.