A250 POTENTIAL OF ADAPTIVE DESIGNS TO ADDRESS CURRENT CHALLENGES IN TRIAL EVALUATION OF TREATMENTS FOR CROHN’S DISEASE

摘要

BackgroundSeveral characteristics of Crohn’s disease, such as varying phenotypes and inconsistent outcome measures can make it a difficult disease to study. Further, in the setting of clinical trials, investigators often face challenges pertaining to poor study recruitment, prohibitive costs, and high placebo rates.