Checkpoint Inhibitors Spur Changes in Trial Design Adaptive studies, novel endpoints, new preclinical models address research challenges

Harper Kristin

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Checkpoint Inhibitors Spur Changes in Trial Design Adaptive studies, novel endpoints, new preclinical models address research challenges

机译：检查点抑制剂试验设计自适应研究的变化，新的终点，新的临床前模型解决了研究挑战

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《Cancer discovery.》 |2017年第11期|共2页
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Harper Kristin;
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正文语种 eng
中图分类肿瘤学;
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1. Pharmacophore Modeling and in Silico Screening Studies to Design Potential KDR Kinase Inhibitors [J] . Xu Dan, Sun Haopeng, Chen Yadong, 中国化学：英文版 . 2011,第006期
2. Pharmacophore Modeling and in Silico Screening Studies to Design Potential KDR Kinase Inhibitors [J] . Xu Dan, Sun Haopeng, Chen Yadong, 中国化学（英文版） . 2011,第006期
3. Checkpoint Inhibitors Spur Changes in Trial Design Adaptive studies, novel endpoints, new preclinical models address research challenges [J] . Harper Kristin Cancer discovery. . 2017,第11期

机译：检查点抑制剂试验设计自适应研究的变化，新的终端，新的临床前模型解决了研究挑战
4. Trial Design and Endpoint Evaluation in Clinical Studies Addressing Chronic Back Pain [J] . Staats Peter S. Spine . 2017,第14Suppla期

机译：解决慢性背痛的临床研究试验设计与终点评估
5. 778?Preclinical study using a glutamatergic signaling and immune-checkpoint inhibitors in a spontaneous melanoma prone mouse model [J] . Kevinn Eddy, Christina Marinaro, Maryam Rasheed, Journal for ImmunoTherapy of Cancer . 2020,第Suppla3期

机译：778？在自发黑色素瘤中使用谷氨酸胶信号和免疫检查点抑制剂的临床前研究易于小鼠模型
6. Pharmacophore Modeling and Virtual Screening Studies of Checkpoint Kinase 1 Inhibitors [C] . Jin-Juan Chen, Ting-Lin Liu, Li-Jun Yang, ICMSI;International conference of molecular simulations and applied informatics technologies . 2010

机译：检查点激酶1抑制剂的药效学建模和虚拟筛选研究
7. Bayesian modeling of combined endpoints for sequentially adaptive design and comfirmatory trial planning. [D] . Wei, Caimiao. 2015

机译：组合端点的贝叶斯建模，用于顺序自适应设计和验证性试验计划。
8. A250 POTENTIAL OF ADAPTIVE DESIGNS TO ADDRESS CURRENT CHALLENGES IN TRIAL EVALUATION OF TREATMENTS FOR CROHN’S DISEASE [O] . L Du, Z Gallinger 2019

机译：A250适应性设计的潜力可以解决对克罗恩病的治疗评估中的当前挑战
9. Checkpoint Inhibitors Spur Changes in Trial Design [O] . 2017

机译：检查点抑制剂试用设计的变化
10. Phase 1 Trial of an Immune Checkpoint Inhibitor plus Stereotactic Ablative Radiotherapy in Patients with Inoperable Stage I Non-Small Cell Lung Cancer. [R] . Kelly, K., Monjazeb, A., Daly, M., 2017

机译：免疫检查点抑制剂加立体定向消融放疗治疗不能手术的I期非小细胞肺癌的1期试验。

Checkpoint Inhibitors Spur Changes in Trial Design Adaptive studies, novel endpoints, new preclinical models address research challenges

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