Usefulness of 131I-SPECT/CT and 18F-FDG PET/CT in Evaluating Successful 131I and Retinoic Acid Combined Therapy in a Patient with Metastatic Struma Ovarii

摘要

Metastatic struma ovarii is an extremely rare disease, and the treatment of choice has not been established. Here, we introduce the case of a 36-year-old female pregnant patient with metastatic struma ovarii. Initial treatment was an exploratory laparotomy to remove multiple peritoneal masses. After delivery, a total thyroidectomy was done for the further ¹³¹I-therapy. ¹³¹I-SPECT/CT and ¹⁸ F-FDG PET/CT showed multiple hepatic metastases and extensive peritoneal seeding nodules. Multiple ¹³¹I and retinoic acid combination therapies were performed, resulting in marked improvement. ¹³¹I-SPECT/CT and ¹⁸ F-FDG PET/CT were quite useful for evaluating the biologic characteristics of the metastases.