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Identification of human immunodeficiency virus type 1 (HIV-1) gp120-binding sites on scavenger receptor cysteine rich 1 (SRCR1) domain of gp340

机译：鉴定人类免疫缺陷病毒1型（HIV-1）gp120结合位点在gp340的富受体半胱氨酸1（SRCR1）域上

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摘要

Backgroundgp340, a member of scavenger receptor cysteine rich family encoded by Deleted in Malignant Brain Tumors 1 (DMBT1), is an important component in innate immune defense. The first scavenger receptor cysteine rich domain (SRCR1) of gp340 has been shown to inhibit HIV-1 infection through binding to the N-terminal flank of the V3 loop of HIV-1 gp120.

机译：Backgroundgp340是富含清除剂受体的半胱氨酸家族的成员，由恶性脑肿瘤1（DMBT1）中的Deleted编码，是先天性免疫防御的重要组成部分。 gp340的第一个清道夫受体富含半胱氨酸结构域（SRCR1）已显示通过与HIV-1 gp120的V3环的N末端侧面结合来抑制HIV-1感染。

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期刊名称 Journal of Biomedical Science
作者
Ying Chu; Jiahuang Li; Xilin Wu; Zichun Hua; Zhiwei Wu;
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作者单位

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年(卷),期 2013(20),1
年度 2013
页码 44
总页数 7
原文格式 PDF
正文语种
中图分类医学史;
关键词
SRCR1 DMBT1 HIV-1 gp120 Automated docking;

机译：SRCR1;DMBT1;HIV-1 gp120;自动对接;

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专利

1. Identification of human immunodeficiency virus type 1 (HIV-1) gp120-binding sites on scavenger receptor cysteine rich 1 (SRCR1) domain of gp340 [J] . Ying Chu, Jiahuang Li, Xilin Wu, Journal of biomedical science. . 2013,第1期

机译：鉴定人类免疫缺陷病毒1型（HIV-1）gp120结合位点在gp340的富半胱氨酸受体1（SRCR1）域上
2. Identification of human immunodeficiency virus type 1 (HIV-1) gp120-binding sites on scavenger receptor cysteine rich 1 (SRCR1) domain of gp340 [J] . Ying Chu, Jiahuang Li, Xilin Wu, Journal of biomedical science. . 2013,第1期

机译：鉴定人类免疫缺陷病毒1型（HIV-1）gp120结合位点在gp340的富半胱氨酸受体1（SRCR1）域上
3. Human Immunodeficiency Virus Type 1 (HIV-1) Transactivator of Transcription through Its Intact Core and Cysteine-Rich Domains Inhibits Wnt/beta-Catenin Signaling in Astrocytes: Relevance to HIV Neuropathogenesis [J] . Henderson Lisa J., Sharma Amit, Monaco Maria Chiara G., The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2012,第46期

机译：人类免疫缺陷病毒1型（HIV-1）转录激活子，通过其完整的核心和富含半胱氨酸的域抑制星形胶质细胞中的Wnt /β-Catenin信号传导：与HIV神经发病相关
4. Identification of HIV-1 gp120-binding sites on SRCR1, a subdomain of gp340 [C] . Nie Chao, Li Jia-Huang, He Xin, International Symposium on Medical and Pharmaceutical Biotechnology(医药生物技术国际研讨会) . 2009

机译：鉴定SRCR1（gp340的一个子域）上的HIV-1 gp120结合位点
5. The role of the transmembrane and cytoplasmic domains of the VPU protein of human immunodeficiency virus type 1 (HIV-1) in the acute CD4+ T cell loss and disease in the simian human immunodeficiency virus (SHIV)/macaque model. [D] . Hout, David Richard. 2006

机译：人类免疫缺陷病毒1型（HIV-1）的VPU蛋白的跨膜和胞质域在猿猴人类免疫缺陷病毒（SHIV）/猕猴模型的急性CD4 + T细胞丧失和疾病中的作用。
6. Human Immunodeficiency Virus Type 1 (HIV-1) Transactivator of Transcription through Its Intact Core and Cysteine-Rich Domains Inhibits Wnt/β-Catenin Signaling in Astrocytes: Relevance to HIV Neuropathogenesis [O] . Lisa J. Henderson, Amit Sharma, Maria Chiara G. Monaco, 2012

机译：人类免疫缺陷病毒1型（HIV-1）转录激活子通过其完整的核心和富含半胱氨酸的域抑制星形胶质细胞中的Wnt /β-Catenin信号传导：与HIV神经发病机制的相关性
7. Identification of human immunodeficiency virus type 1 (HIV-1) gp120-binding sites on scavenger receptor cysteine rich 1 (SRCR1) domain of gp340 [O] . Ying Chu, Jiahuang Li, Xilin Wu, 2013

机译：鉴定人类免疫缺陷病毒1型（HIV-1）gp120结合位点在gp340的富受体半胱氨酸1（SRCR1）域上

Identification of human immunodeficiency virus type 1 (HIV-1) gp120-binding sites on scavenger receptor cysteine rich 1 (SRCR1) domain of gp340

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