Evaluation of spirometry findings with severity of coronary artery disease in smoker patients undergoing angiography in military hospital during 2019-2020

摘要

Background: Coronary heart disease is the most common cardiovascular worldwide, and some factors can affect the prognosis of this disease. So, in this study, we aimed to examine the relationship between spirometry and cardiovascular risk factors in patients undergoing coronary angiography who were referred to military hospitals. Methods: In this cross-sectional study, 200 smokers referred to military hospital for angiography, were enrolled in terms of the inclusion and exclusion criteria between 2019 and 2020. The severity of the coronary artery involvement was determined using Gensini score. The relationship among spirometry and the forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and FEV1/FVC with other variables including lipid profile, demographic findings, blood pressure, physical activity, and severity of coronary artery involvement were also exanimated. Results: The frequency of severity of coronary involvement were reported as 3.5% with 25% involvement, 7% with 26-50% involvement, 5.5% with 51-75% involvement, 27.5% with 76-90% involvement, 47% with 91-99% involvement, and 9.5% with 100% involvement. In addition, there was no significant relationship between severity of coronary involvement and FEV1 and FVC (P>0.05). However, there was a significant difference between the groups based on FEV1/FVC (P=0.003), in which the mean of FEV1/FVC was significantly lower in higher severity of coronary involvement compared to lower severity of coronary involvement. There were significant relationships between severity of coronary involvement and body mass index, fasting blood sugar, high-density lipoprotein and low-density lipoprotein, cholesterol, triglyceride, waist circumference, systolic blood pressure, diastolic blood pressure, physical activity, and smoking (P<0.05). Conclusion: There is an association between pulmonary diseases and coronary disease, in which the increased coronary involvement severity is associated with the decreased FEV1/FVC.