Adjuvant Radiotherapy Significantly Increases Neck Control and Survival in Early Oral Cancer Patients with Solitary Nodal Involvement: A National Cancer Registry Database Analysis

摘要

For early oral cancer with solitary nodal metastasis, the role of adjuvant radiotherapy on neck control and survival remains controversial. Based on our national cancer registry database, univariate and multivariable analysis showed that adjuvant radiotherapy significantly associated with better 5-year OS and DFS compared to patients who received surgery alone. Stratified analysis indicated the greatest survival advantage for 5-year OS and DFS in those with pT2 classification and non-tongue disease. Moreover, adjuvant radiotherapy significantly protected against neck recurrence.