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Drug-induced hypersensitivity syndrome like reaction with angioedema and hypotension associated with BRAF inhibitor use and antecedent immune checkpoint therapy

机译：药物诱导的过敏症综合征类似于与血管内膜的反应和与BRAF抑制剂使用相关的低血压和前一种免疫检查点治疗

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摘要

Clinical characteristics of DLR in patients after BRAF/MEK inhibition following ICI and their treatment and re-challenge response.

机译：伊索综合症及其治疗及再攻击反应后BRAF / MEK抑制后DLR患者的临床特征及其治疗。

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期刊名称 JAAD Case Reports
作者
Jasmine Rana; Nolan J. Maloney; Kerri E. Rieger; Silvina B. Pugliese; Jenna L. Strelo; Anne Liu; Lisa C. Zaba; Bernice Y. Kwong;
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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 5
原文格式 PDF
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关键词

机译：BRAF;BRAF抑制剂;CTLA4;DABRAFENIB;DIHS;连衣裙;ICI;IMI;免疫检查点治疗;IMIN;IRAE;IRCAE;oncoderm;PD1;PD-1;PD-1;PD-1;皮疹;vemurafenib;

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专利

1. Posterior Reversible Encephalopathy Syndrome (PRES) and Drug-Induced Hypersensitivity Syndrome (DIHS) following Immunotherapy and BRAF/MEK Inhibition with Continued Response in Metastatic Melanoma [J] . J. M. Sabile, D. J. Grider, K. A. Prickett, Case Reports in Oncological Medicine . 2021,第a期

机译：免疫疗法和BRAF / MEK抑制在转移黑色素瘤中持续反应后，后逆转脑病综合征（PRES）和药物诱导的超敏反应综合征（DIHS）
2. Patterns of treatment and BRAF testing with immune checkpoint inhibitors and targeted therapy in patients with metastatic melanoma presumed to be BRAF positive [J] . Ghate Sameer, Ionescu-Ittu Raluca, Burne Rebecca, Melanoma research . 2019,第3期

机译：用免疫检查点抑制剂和靶向治疗的治疗和BRAF检测模式，所述转移性黑素瘤的靶向治疗假定BRAF阳性
3. Immune reconstitution inflammatory syndrome observed in the setting of drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS) [J] . Yoko Kano, Yukiko Ushigome, Chiho Horie, Clinical and Translational Allergy . 2014,第SUPPLEMENTa3期

机译：在具有嗜酸性粒细胞增多和全身症状的药物诱发的超敏反应综合征/药物反应中观察到免疫重建炎症综合征（DIHS / DRESS）
4. ENGINEERING AND PRE-CLINICAL EVALUATION OF A HUMAN ENZYME IMMUNE CHECKPOINT INHIBITOR FOR CANCER THERAPY [C] . Everett Stone, John Blazek, Christos Karamitros, Enzyme Engineering Conference . 2018

机译：癌症治疗人酶免疫检查点抑制剂的工程与临床评价
5. Involvement of Th17 Pathway in Adverse Drug Reactions: Mechanistic Investigation of Drug-Induced Autoimmunity and Drug-induced Liver Injury. [D] . Zhu, Ervin Xu. 2012

机译：Th17途径参与药物不良反应：药物诱发的自身免疫和药物诱发的肝损伤的机制研究。
6. Posterior Reversible Encephalopathy Syndrome (PRES) and Drug-Induced Hypersensitivity Syndrome (DIHS) following Immunotherapy and BRAF/MEK Inhibition with Continued Response in Metastatic Melanoma [O] . J. M. Sabile, D. J. Grider, K. A. Prickett, 2021

机译：免疫疗法和BRAF / MEK抑制在转移黑色素瘤中持续反应后后逆转脑病综合征（PRES）和药物诱导的超敏反应综合征（DIHS）
7. Case Report: A Case of Trimethoprim/Sulfamethoxazole-Triggered Hypotensive Shock: Cytokine Release Syndrome Related to Immune Checkpoint Inhibitors and Drug-Induced Hypersensitivity Syndrome [O] . Tetsuya Urasaki, Makiko Ono, Toshiaki Mochizuki, 2021

机译：案例报告：致苯甲肽/磺胺甲恶唑触发的低血压休克病例：细胞因子释放综合征有关免疫检查点抑制剂和药物诱导的过敏综合征

Drug-induced hypersensitivity syndrome like reaction with angioedema and hypotension associated with BRAF inhibitor use and antecedent immune checkpoint therapy

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