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Hepatitis C virus: Current steps toward elimination in Germany and barriers to reaching the 2030 goal

机译:丙型肝炎病毒:目前在德国消除的步骤和达到2030年的障碍

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摘要

Hepatitis C virus (HCV) affects over 70 million people globally, with an estimated 399 000 HCV‐related deaths in 2016. The World Health Organization (WHO) has set a goal to eliminate HCV by 2030. Despite the availability of direct‐acting antivirals—highly effective and well‐tolerated therapies for HCV—many patients infected with HCV in Germany have not initiated treatment, including a majority of those who are aware of their positive diagnosis. Barriers to screening, diagnosis, and treatment are major factors taking many countries off track for HCV elimination by 2030. Identifying country‐specific barriers and challenges, particularly in at‐risk populations such as people who inject drugs or men who have sex with men, has the potential to create tailored programs and strategies to increase access to screening or treatment and engage at‐risk populations. This review aims to report the current steps toward HCV elimination in Germany, the country‐specific barriers and challenges that will potentially prevent reaching the 2030 HCV elimination goal and describe good practice examples to overcome these barriers.
机译:丙型肝炎病毒(HCV)在全球范围内影响超过7000万人,估计2016年有399 000个相关的死亡。世界卫生组织(世卫组织)设定了2030年消除HCV的目标。尽管有可用性的抗病毒率 - 在德国患有HCV的HCV患者的高效且耐受良好的疗法未开始治疗,包括大多数了解其积极诊断的人。筛选,诊断和治疗的障碍是将许多国家偏离HCV消除追踪的主要因素到2030年。确定特定国家的障碍和挑战,特别是在风险的人口,例如注入与男性发生性关系的人或男性的人群,有可能创建量身定制的计划和策略,以增加对筛选或治疗的获取,并参与风险的人口。本综述旨在报告德国HCV消除的目前的步骤,国家特定的障碍和挑战,可能会阻止达到2030 HCV消除目标,并描述克服这些障碍的良好实践例子。

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