Influence of preoperative corticosteroid treatment on rate of diagnostic surgeries in primary central nervous system lymphoma: a multicenter retrospective study

摘要

Typical MRI of PCNSL. Preoperative MRI showing multifocal contrast enhancing lesions on T1-weighted sequences (a). The patient received 12 mg dexamethasone per day for 8 days in a peripheral hospital and regression was visible on navigational MRI (b). CST was then paused 2 days prior to surgery. MRI of a patient with a large bifrontal lesion affecting the corpus callosum (c). The patient received 12 mg dexamethasone per day for 3 days following first MRI. The CST was paused immediately after transfer of the patient. Second MRI was performed after 4 days off of CST showing distinct progression (d)