首页> 美国卫生研究院文献>Neuro-oncology Advances >Calculating the net clinical benefit in neuro-oncology clinical trials using two methods: quality-adjusted survival effect sizes and joint modeling

【2h】

Calculating the net clinical benefit in neuro-oncology clinical trials using two methods: quality-adjusted survival effect sizes and joint modeling

机译：使用两种方法计算神经肿瘤临床试验中的净临床效益：质量调整的存活效果尺寸和联合建模

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

Two methods combining survival and health-related quality of life (HRQoL) data in glioma trials to calculate the “net clinical benefit” were evaluated: Quality-adjusted effect sizes (QASES) and joint modeling (JM).

机译：两种方法将生存和健康相关的生命质量（HRQOL）数据中的胶质瘤试验中的寿命（HRQOL）数据进行了评价：评价：质量调整的效果尺寸（Qases）和联合建模（JM）。

著录项

期刊名称 Neuro-oncology Advances
作者
Marijke B Coomans; Linda Dirven; Neil K Aaronson; Brigitta G Baumert; Martin van den Bent; Andrew Bottomley; Alba A Brandes; Olivier Chinot; Corneel Coens; Thierry Gorlia; Ulrich Herrlinger; Florence Keime-Guibert; Annika Malmström; Francesca Martinelli; Jeff A Sloan; Roger Stupp; Andrea Talacchi; Michael Weller; Wolfgang Wick; Jaap C Reijneveld; Martin J B Taphoorn;
展开▼
作者单位

展开▼
年(卷),期 2020(2),1
年度 2020
页码 vdaa147
总页数 9
原文格式 PDF
正文语种
中图分类肿瘤学;放射医学;影像诊断学;
关键词

机译：胶质瘤;联合模型;净临床效益;生活质量;生存;

相似文献

外文文献
中文文献
专利

1. Incremental net benefit in randomized clinical trials with quality-adjusted survival. [J] . Willan AR, Bingshu Chen E, Cook RJ, Statistics in medicine . 2003,第3期

机译：在质量调整后的生存率的随机临床试验中增加的净收益。
2. Survival benefit of mantle cell lymphoma patients enrolled in clinical trials; a joint study from the LYSA group and French cancer registries [J] . Alix Augustin, Steven Le Gouill, Rémy Gressin, Journal of Cancer Research and Clinical Oncology . 2018,第4期

机译：患有临床试验的地幔细胞淋巴瘤患者的生存益处; Lysa组和法语癌症注册管理机构的联合研究
3. Commentary on: Survival benefit of mantle cell lymphoma patients enrolled in clinical trials; a joint study from the LYSA group and French cancer registries [J] . Juste Aristide Goungounga, Roch Giorgi Journal of Cancer Research and Clinical Oncology . 2018,第4期

机译：评注：临床试验中患者患者的伴细胞淋巴瘤患者的生存益处; Lysa组和法语癌症注册管理机构的联合研究
4. Hybrid research simulation modeling for making decisions on sample size and power of randomized clinical trials considering expected net benefits [C] . Ismail Abbas Simulation Conference . 2017

机译：混合研究模拟模型，用于在考虑预期净收益的情况下决定随机临床试验的样本量和功效
5. A comparison of adaptive methods for the analysis of clinical trials: A Bayes-ide window into some frequent-ly underutilized methods for clinical trials analysis. [D] . Pressman, Alice Rogot. 2009

机译：用于临床试验分析的自适应方法的比较：进入贝叶斯窗口，进入一些经常未被充分利用的临床试验分析方法。
6. OS7.4 Calculating the net clinical benefit in brain tumor clinical trials by combining survival and health-related quality of life data using two methods: quality adjusted survival effect sizes (QASES) and joint modelling (JM) [O] . M Coomans, L Dirven, A Bottomley, 2019

机译：OS7.4通过使用两种方法将生存和健康相关的生活质量组合来计算脑肿瘤临床试验中的净临床效益：质量调整的存活效果尺寸（Qase）和联合建模（JM）
7. Poster Session 3The imaging examination and quality assessmentP626Value of mitral and tricuspid annular displacement to assess the interventricular systolic relationship in severe aortic valve stenosis : a Pilot studyP627Follow-up echocardiography in asymptomatic valve disease: assessing the potential economic impact of the European and American guidelines in a dedicated valve clinic, compared to standard care.P628The tricuspid valve: identification of optimal view for assessing for prolapseP629Right atrial volume by two-dimensional echocardiography in healthy subjectsP630Disturbance of inter and intra atrial conduction assessed by tissue doppler imaging in patients with medicaly controlled hypertension and prehypertension.P631Liver stiffness by shear wave elastography, new noninvasive and quantitative tool for acute variation estimation of central venous pressure in real-time?P632Weak atrial kick contribution is associated with a risk for heart failure decompensationP633Usefulness of wave intensity analysis in predicting the response to cardiac resynchronization therapyP634Early subclinical left ventricular systolic and diastolic dysfunction in gestational hypertension and preeclampsiaP635Clinical comparison of three different echocardiographic methods for left ventricular ejection fraction and LV end diastolic volume measurementP636Assessment of right ventricular-arterial coupling parameters by 3D echocardiography in patients with pulmonary hypertension receiving specific vasodilator therapyP637Prediction of right ventricular failure after left ventricular assist device implant: assessing usefulness of standard and strain echocardiographyP638Kinematic analysis of diastolic function using the novel freely available software Echo E-waves - feasibility and reproducibilityP639Evaluation of coronary flow velocity by Doppler echocardiography in the treatment of hypertension with the ARB: correlation to the histological cardiac fibrosisP640The clinical significance of limited apical ischaemia and the prognostic value of stress echocardiography - A contemporary study from a high volume centerP641Effects of intermediate stenosis of left anterior descending coronary artery on survival in patients with chronic total occlusion of right coronary arteryP642Left ventricular remodeling after a first myocardial infarction in patients with preserved ejection fraction at dischargeP643Left atrial size and acute coronary syndromes. Let is make simple.P644Influence of STEMI reperfusion strategy on systolic and diastolic functionP645Aortic valve resistance risk-stratifies low-gradient severe aortic stenosisP646Does permanent pacemaker implantation complicate the prognosis of patients after transcatheter aortic valve implantation?P647Influence of metabolic syndrome and diabetes on progression of calcific aortic valve stenosis - The COFRASA - GENERAC StudyP648Low referral for aortic valve replacement accounts for worse long-term outcome in low versus high gradient severe aortic stenosis with preserved ejection fractionP649The impact of right ventricular function from aortic valve replacement: A randomised study comparing minimally invasive aortic valve surgery and conventional open heart surgery [O] . T. Ota, DNS Senaratne, NK. Preston, 2016

机译：海报课程3年度成像检查和质量评估P626尺寸二尖瓣环形位移，评估严重主动脉瓣狭窄中的间隔收缩系统关系：无症状瓣膜病的先导术627推翻超声心动图：评估欧洲和美国指南的潜在经济影响专用阀门诊所，与标准Care.P628相比，Tricuspid阀门：鉴定通过在医疗主题的Hystantsp630中，通过组织多普勒成像在医疗和术语中的癌细胞癌和术语患者进行评估，通过二维超声心动图进行评估的最佳视图。 .p631抗剪力波弹性凝视，新的非侵入性和定量工具，用于实时急性变异估计中央静脉压力的急性变化？P632Weak心房踢贡献与心力衰竭分数的风险有关波强度分析预测心脏重新同步的响应治疗634亚临床左心室收缩和舒张性功能障碍，妊娠期高血压分数的三种不同超声心动仪和LV端舒张型方法的比较，3D超声心动图右心室凝血率测量3636分类在患有肺动脉高压的患者中，左心室辅助装置植入后接受特异性血管扩张器治疗637预测右心室失效：评估使用新颖的自由可用的软件回声电子波的标准和菌株超声心动图338云分析的标准和菌株超声心动图638云分析 - 可行性和再现冠状动脉速度的可行性和再现率。多普勒超声心动图在治疗高血压与arb中：相关性与组织学心肌纤维化p640的相关性李的临床意义紧张的缺血性和应激超声心动图的预后价值 - 一种高批量中心的当代研究，来自左前期下降冠状动脉中间狭窄患者中间狭窄患者急性闭塞患者患者患者患者第一次心肌梗死后的慢性冠状动脉间梗死患者存活的现代研究排出的射血分数在排出的343夜心房尺寸和急性冠状动脉综合征处。让令人生意的是STEMIESTOMELETERIC功能的STEMIEST.P644。在收缩和舒张功能上进行STEMI和舒张型阀门电阻危险危险率低梯度严重主动脉鼻窦646doe永久性起搏器植入使经截觉管主动脉瓣植入后的患者预后复杂化吗？P647型综合征和糖尿病患者的进展主动脉瓣狭窄 - Cofrasa - Generac STOMP648LOW用于主动脉瓣膜置换术的转诊表明，低梯度严重主动脉狭窄的更差的长期结果，并具有射血瓣膜置换术射精术中的抗锻术术造成的影响：随机研究比较微创主动脉阀门手术和常规开放式心脏手术
8. Coordinating Center Models Project: A Study of Coordinating Centers in Multicenter Clinical Trials. XIV. Enhancement of Methodological Research in the Field of Clinical Trials [R] . 1979

机译：协调中心模型项目：多中心临床试验中的协调中心研究。十四。加强临床试验领域的方法论研究

Calculating the net clinical benefit in neuro-oncology clinical trials using two methods: quality-adjusted survival effect sizes and joint modeling

摘要

著录项

相似文献

相关主题

期刊订阅