Abstract 152: Adipose-derived Stromal Cells Within Transplanted Fat Hone To Blood Vessels And Assume A Pericyte Structure

摘要

Purpose: Fat grafting can restore volume defects and improve the texture, quality, and appearance of overlying skin. The adipose-derived stromal cells (ASCs) within transplanted fat are thought to drive these regenerative effects, either by direct differentiation or by paracrine signaling. The survival and differentiation fate of transplanted ASCs post grafting, however, remains incompletely understood. We therefore performed lineage tracing of transplanted human ASCs in vivo using a mouse model of fat grafting.