BACKGROUND: Many studies have shown that cell-assisted lipotransfer promotes the survival of fat implants, but there are few studies exploring stromal vascular fraction (SVF) -assisted fat transplantation for improving facial skin quality. OBJECTIVE: To evaluate the clinical effect of autologous adipose-derived SVF-assisted autologous fat transplantation in the improvement of facial skin quality. METHODS: From September 2016 to June 2018, in the Plastic and Cosmetic Center, the Affiliated Hospital of Xuzhou Medical University, 20 patients were recruited and then randomly divided into experimental group and control group, namely SVF-assisted fat transplantation and simple fat transplantation, respectively. A VISIA skin detector was used to detect facial skin quality of patients preoperatively and 6 months postoperatively, including spots, wrinkles, texture, pores, ultraviolet spots, brown spots, couperose skin and porphyrin. RESULTS AND CONCLUSION: The effect of improvement in wrinkles and texture in the experimental group was better than that of the control group, and the difference was statistically significant (P < 0.05). In terms of spots, pores and couperose skin, the therapeutic effect in the experimental group was better than that in the control group, but the difference was not statistically significant (P> 0.05). There was no significant difference between the two groups in the improvement of ultraviolet spot and brown spots. The porphyrin was not affected by the subjects. To conclude, SVF can promote the effect of fat transplantation in the improvement of facial skin quality.%背景:研究表明细胞辅助脂肪移植能够促进移植物的存活, 但研究其改善面部皮肤质量的报道较少.目的:观察基质血管组分辅助自体脂肪移植改善面部皮肤质量的临床应用效果.方法:2016年9月至2018年6月在徐州医科大学附属医院整形美容中心招募患者.20例患者随机分为试验组和对照组, 即基质血管组分辅助脂肪移植与单纯脂肪移植.VISIA皮肤检测仪检测患者移植前及移植后6个月的面部皮肤质量, 包括斑点、皱纹、纹理、毛孔、紫外线色斑、棕色斑、红色区、紫质8个皮肤指标.结果与结论:试验组在皱纹和纹理方面改善值高于对照组, 差异有显著性意义 (P <0.05) .在斑点、毛孔及红色区方面, 试验组治疗效果改善值高于对照组, 但差异无显著性意义 (P> 0.05) .在紫外线色斑、棕色斑方面, 两组治疗效果改善值差异无显著性意义 (P> 0.05) .紫质未受研究对象的影响.结果表明, 基质血管组分能够提升脂肪移植在改善面部皮肤质量中的效果.
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