Medium- and long-term functional behavior evaluations in an experimental focal ischemic stroke mouse model

摘要

Effect of distal middle cerebral artery (DMCA) occlusion on mechanical and thermal hyperalgesia in mice (a–e). Mechanical hyperalgesia assessment with a 0.4 g vF filament: right (a) and left hind paw (c). Mechanical hyperalgesia assessment with a 1.0 g vF filament: right (b) and left hind paw (f). e Thermal hyperalgesia assessment (48 °C). Each group represents the average of 8 animals and the vertical bars indicate the standard deviation. 7 days; 28 days: 7 or 28 days after DMCA occlusion. Two-way ANOVA followed by the Bonferroni test. vF: von Frey. *p < 0.05