Allogeneic human umbilical cord Wharton’s jelly stem cells increase several-fold the expansion of human cord blood CD34+ cells both in vitro and in vivo

摘要

MSC properties of hWJSCs. A (a) Low magnification and (b) high magnification of hWJSCs showing plastic adherence in culture and a stellate morphology. B hWJSCs express MSC markers such as CD29, CD44, CD73, CD90, CD105, and HLA-ABC but lack expression of hematopoietic markers like CD14, CD19, CD34, CD45, and HLA-DR. C hWJSCs differentiate into adipogenic, osteogenic and chondrogenic lineages in vitro