Intensive fever control using a therapeutic normothermia protocol inpatients with febrile early septic shock: A randomized feasibility trial andexploration of the immunomodulatory effects

摘要

Fever control has been shown to reduce short-term mortality in patients withseptic shock. This study aimed to explore the feasibility of early intensivefever control in patients with septic shock and to assess theimmunomodulatory effects of this intervention.