Patients with pretreatment leukoencephalopathy and older patients have more cognitive decline after whole brain radiotherapy

摘要

Study methodology. WMH volumes were contoured and scored using the Fazekas visual rating scale on pre-treatment T2-weighted MRI sequences. Changes in MoCA score after whole brain radiotherapy were assessed for associations with age, WMH volume and Fazekas scores. MoCA Montreal Cognitive Assessment, FLAIR fluid attenuation inversion recovery, dWMH deep white matter hyperintensity, pvWMH periventricular white matter hyperintensity