Toxicity evaluation of an essential oil mixture from the Cretan herbs thyme Greek sage and Cretan dittany

摘要

The effect of CAPeo on a creatinine (mg/dl), urea (mg/dl), AST(U/L), and ALT(U/L) levels, and b the neutrophil to lymphocyte ratio was examined 24 h after treatment. Two different CAPeo doses were tested: 10X and 40X of D1 (the human dose adjusted for rat metabolism) both in male (n = 4) and female (n = 4). The CAPeo doses were given (once) to animals by gavage and blood samples were collected at time 0 and 24 h. Data are represented as mean ± s.d. Asterisk denotes statistical significance (t-test), p < 0.05.