78 Effects of Isomaltooligosaccharide and Bacillus supplementation on sow performance serum metabolite and oxidative status in serum and placenta

摘要

This study investigated the effects of Isomaltooligosaccharide (IMO) and Bacillus supplementation on sow performance, serum metabolite and oxidative status in serum and placenta. One hundred and thirty multiparous gestating sows with similar body condition were randomly allocated to five groups (n = 26), receiving basal diet (CON group) or basal diet supplemented with 0.5% IMO (IMO group), 0.5% IMO and 0.02% Bacillus subtilis (IMO+S group), 0.5% IMO and 0.02% Bacillus licheniformis (IMO+L group), and 0.5% IMO, 0.02% Bacillus subtilis and Bacillus licheniformis (IMO+S+L group), respectively. The reproductive performance of sows was recorded. During farrowing, serum of sow from the ear vein and umbilical vein were collected for determining the metabolite and antioxidatant capacity. The placenta also was collected to determine antioxidant capacity. Statistical analysis was performed with covariance analysis and one-way analysis of variance followed by a Duncan multiple range test with SPSS 21.0. The results showed that no difference was observed in litter size among all groups (P > 0.05), while the average piglet birth weight was improved in all treatments and the placental efficiency was increased in IMO+S group and IMO+S+L group compared with CON group (P < 0.05). IMO+S+L increased low-density lipoprotein cholesterol (LDL-C) and reduced total cholesterol (TC) concentration in umbilical venous serum (P < 0.05). In addition, sows in all treatment groups had greater malondialdehyde (MDA) levels in umbilical venous serum compared with CON group (P < 0.05). Total antioxidant capacity (T-AOC) of placenta was increased in IMO+L group and IMO+S+L group (P < 0.05). Moreover, the concentration of growth hormone (GH) in umbilical venous serum was improved (P < 0.05) in all treatments group. In conclusion, IMO and Bacillus supplementations during late gestation changed the lipid and protein metabolism of sows, improved the placental antioxidant capacity, increased GH levels in umbilical venous serum, ultimately improved the piglet birth weight and placental efficiency.