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Pyrazinamide Resistance and Mutation Patterns Among Multidrug-Resistant Mycobacterium tuberculosis from Henan Province

机译：河南省多药抗性结核分枝杆菌的吡嗪酰胺抗性和突变模式

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摘要

This study was designed to identify the phenotypic and genotypic characteristics of pyrazinamide (PZA) resistance among multidrug-resistant Mycobacterium tuberculosis (MDR-TB) from Henan and to evaluate the efficacy of pncA, rpsA, and panD mutations in predicting PZA resistance.

机译：本研究旨在鉴定来自河南多药抗性结核（MDR-TB）的吡嗪酰胺（PZA）抗性的吡嗪酰胺（PZA）抗性的表型和基因型特征，并评估PNCA，RPSA和PAll突变预测PZA抗性的疗效。

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期刊名称 Infection and Drug Resistance
作者
Jie Shi; Ruyue Su; Danwei Zheng; Yankun Zhu; Xiaoguang Ma; Shaohua Wang; Hui Li; Dingyong Sun;
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作者单位

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年(卷),期 2020(-1),-1
年度 2020
页码 -1
总页数 13
原文格式 PDF
正文语种
中图分类药学;
关键词

机译：结核分枝杆菌;

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专利

1. Pyrazinamide Resistance and Mutation Patterns Among Multidrug-Resistant Mycobacterium tuberculosis from Henan Province [J] . Jie Shi, Ruyue Su, Danwei Zheng, Infection and Drug Resistance . 2020,第1期

机译：河南省多药抗性结核分枝杆菌的吡嗪酰胺抗性和突变模式
2. Detection of Novel Gene Mutations Associated with Pyrazinamide Resistance in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates in Southern China [J] . HM Adnan Hameed, Yaoju Tan, Mahmudul Islam, Infection and Drug Resistance . 2020,第1期

机译：南方南部多药抗性结核临床分离株吡嗪酰胺抗性的新型基因突变检测
3. Relationship between pyrazinamide resistance, loss of pyrazinamidase activity, and mutations in the pncA locus in multidrug-resistant clinical isolates of Mycobacterium tuberculosis. [J] . Mestdagh M, Fonteyne PA, Realini L, Antimicrobial agents and chemotherapy. . 1999,第9期

机译：吡嗪酰胺耐药性，吡嗪酰胺酶活性丧失与结核分枝杆菌多药耐药临床分离株中pncA基因座突变之间的关系。
4. Mechanistic analysis elucidating the relationship between Lys96 mutation in Mycobacterium tuberculosis pyrazinamidase enzyme and pyrazinamide susceptibility [C] . Chakshu Vats, Jaspreet Kaur Dhanjal, Sukriti Goyal, Asia-Pacific Bioinformatics Conference . 2015

机译：机械分析阐明了结核分枝杆菌吡嗪酰胺酶和吡嗪酰胺敏感性术中Lys96突变的关系
5. A Search for Novel Pyrazinamide Resistance Genes in Mycobacterium tuberculosis [D] . Tran, Duke A. 2017

机译：在结核分枝杆菌中寻找新的吡嗪酰胺抗性基因
6. Detection of Novel Gene Mutations Associated with Pyrazinamide Resistance in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates in Southern China [O] . HM Adnan Hameed, Yaoju Tan, Md Mahmudul Islam, 2020

机译：南方南部多药抗性结核临床分离株吡嗪酰胺抗性的新型基因突变检测
7. >Pyrazinamide Resistance and Mutation Patterns Among Multidrug-Resistant Mycobacterium tuberculosis from Henan Province [O] . Jie Shi, Ruyue Su, Danwei Zheng, 2020

机译：河南省多药物抗性抗性抗纤维酰胺抗性和突变模式

Pyrazinamide Resistance and Mutation Patterns Among Multidrug-Resistant Mycobacterium tuberculosis from Henan Province

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